Disturbances in retinal blood flow and oxygenation are believed to be involved in several diseases which may severely impair vision. Those include some of the most common eye diseases such as retinal vascular occlusions1,2, glaucoma3-5 and diabetic retinopathy.6,7

Studies suggest that treatment, such as laser treatment and vitrectomy, may improve retinal oxygenation.1,7,8

Oxymap provides innovative equipment which allows eye-care professionals and clinical researchers to gain a deep insight into the retinal physiology in health and disease.

The Oxymap T1 Installed on Top of the Topcon TRC-50DX Fundus Camera

The Oxymap T1 Installed on Top of the Topcon TRC-50DX Fundus Camera

References

1. Pournaras CJ, Tsacopoulos M, Strommer K, Gilodi N, Leuenberger PM. Scatter photocoagulation restores tissue hypoxia in experimental vasoproliferative microangiopathy in miniature pigs. Ophthalmology. 1990;97:1329-1333.
2. Stefánsson E, Novack RL, Hatchell DL. Vitrectomy prevents retinal hypoxia in branch retinal vein occlusion. Invest Ophthalmol Vis Sci. 1990 Feb;31(2):284-9.
3. Mozaffarieh M, Grieshaber MC, Flammer J. Oxygen and blood flow: players in the pathogenesis of glaucoma. Mol Vis. 2008 Jan 31;14:224-33.
4. Grieshaber MC, Flammer J. Blood flow in glaucoma. Curr Opin Ophthalmol. 2005 Apr;16(2):79-83.
5. Beach J, Ning J, Khoobehi B. Oxygen saturation in optic nerve head structures by hyperspectral image analysis. Curr Eye Res. 2007 Feb;32(2):161-70.
6. Linsenmeier RA, Braun RD, McRipley MA, Padnick LB, Ahmed J, Hatchell DL, McLeod DS, Lutty GA. Retinal hypoxia in long-term diabetic cats. Invest Ophthalmol Vis Sci. 1998 Aug;39(9):1647-57.
7. Stefánsson E. Ocular oxygenation and the treatment of diabetic retinopathy. Surv Ophthalmol. 2006 Jul-Aug;51(4):364-80.
8. Yu DY, Cringle SJ, Su E, Yu PK, Hamayun MS, Dorin G. Laser-induced changes in intraretinal oxygen distribution in pigmented rabbits. Invest Ophthalmol Vis Sci. 2005 Mar;46(3):988-99.

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